Reishi Hot Water Extract vs. Alcohol Extract

By Dr. Markho Rafael

Medicinal mushrooms have been immensely popular in Asia for millennia. Today, Americans are waking up to these powerful nutraceuticals. In the wake of this new awareness follow issues of product quality claims made by competing brands.

All medicinal mushroom species are plagued by this. Most fiercely debated is red reishi (Ganoderma lucidum), the most popular of all medicinal mushrooms. So this article will primarily focus on that species, but it's generally applicable to all species of medicinal mushrooms.

An obvious caution is to stay away from cheap, mass-produced reishi. It may be merely dried and pulverized. In order to be medicinal, the mushroom cell-wall has to be broken down. Mass-produced reishi may be mostly inert and ineffective.

But even among the truly effective therapeutic brands, which are plentiful, there are important differences. Each seems to claim superiority over other brands, not surprisingly, because why else would anyone buy them? This article aims to clarify the confusion of conflicting and sometimes misleading information that is out there.

Below are three common methods for extracting medicinal compounds from reishi. Each method results in different compounds. All groups have been shown to have therapeutic effects in scientific studies.

1. Water Extraction, Hot (polysaccharides and more)

2. Alcohol Extraction (triterpenoids, etc.)

3. Fermented (arabinoxylanes, etc.)

Polysaccharides have been shown to possess powerful anti-tumor qualities through enhancing the immune system and by inhibiting blood profusion through tumors. They are also strong antioxidants. [1]

Through alcohol extraction, we get triterpenoids, a large group of lipids with many sub-groups. Research shows triterpenoids help regulate clotting, blood pressure and cholesterol. More importantly, they are the anti-inflammatory compounds that are the reason why reishi often gets recommended for arthritis, asthma and allergies. [1]

Finally, by fermenting the red reishi, the original medicinal compounds break down to form new compounds with unique healing properties. These "secondary metabolites" have among other things been shown to be immune enhancing and help regulate blood sugar, as well as having unique anti-tumor properties. [2]

This article is intended to give general guidelines to help you choose an effective reishi product, not to recommend any particular brand. But there are at least two reishi companies on the market which both state only hot water extract is useful while alcohol extracts are of no value.

They do that, of course, because they wish to sell their products. However, there is no scientific validity to those claims. All three extraction methods listed above yield important medicinal compounds.

To determine if a brand of reishi (or Ganoderma) contains all the important medicinal compounds from the mushroom, find out if it utilizes both alcohol and hot water extraction. An additional plus would be if it also includes fermented reishi.

Last but not least, remember to look at the form the reishi comes in. If the reishi is able to dissolve completely in water-based drinks like coffee, it's a safe bet that it only contains the water-soluble polysaccharides. An excellent choice as far as coffee goes but an incomplete reishi supplement because it does not include the anti-inflammatory triterpenoid compounds.

On the other hand, alcohol tinctures can actually contain both water soluble polysaccharides and alcohol soluble triterpenoids. The way you know is that the polysaccharides will fall out of solution because of the alcohol, and will make the tincture cloudy. That's alright though; you just need to shake before you take. Capsules and tablets may be one or the other or both. The only way to know is ask the manufacturer or read their information.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L, 2007. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnology Annu Rev 13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresource Technology 2009 Mar;100(5):1852-9. - 30246

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